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Figure 3 | Genome Biology

Figure 3

From: Mapping of disease-associated variants in admixed populations

Figure 3

The effect of marker density on detecting ancestry switches. The number of ancestry switches detected as a function of marker density for the individual with the largest number of ancestry switches (n = 737) among 1,976 African Americans [17]. The continuous red line indicates the sparse panel of 1,943 ancestry-informative markers [18]. The dashed red line indicates saturation at 177,000 random markers, after which more markers provide no additional information regarding the number of ancestry switches. For admixed African Americans, high-throughput genotyping of approximately 1 million markers using commercially available microarrays is sufficient to extract all of the information on local ancestry.

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