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Figure 1 | Genome Biology

Figure 1

From: Mapping of disease-associated variants in admixed populations

Figure 1

Schematic representation of population stratification and admixture. Population stratification can confound analysis of the meta-population in Generation 0 if allele frequencies differ between the two parental populations. Admixed individuals are generated by interbreeding among previously isolated populations. In subsequent generations, due to the cumulative effect of meioses, ancestry switches (that is, changes in ancestry in the interval between two markers) accumulate and chromosomes become mosaics of ancestry.

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