Figure 5

Relative performance of HTP datasets in identifying known kinase-target pairs. Number of gold-standard kinase-substrate pairs identified in each dataset is plotted against the fold-enrichment of kinase-substrate (K-S) pairs found in each dataset. Red, biochemical; green, physical; blue, genetic. See text for details. SDL, synthetic dosage lethality; SGA, synthetic genetic array; SL, synthetic lethality; SSup, synthetic suppression. SS refers to the source for the SDL, SL, SSup data reported in Sharifpoor et al (Functional wiring of the yeast kinome revealed by global genetic network motif analysis, submitted).