| |
Control
|
0.16 μM IQ-143
|
1.25 μM IQ-143
|
|---|
| |
Mean (μg/ml)
|
SD
|
Mean (μg/ml)
|
SD
|
% of control
|
Mean (μg/ml)
|
SD
|
% of control
|
|---|
|
NAD
|
42.19
|
2.44
|
35.68**
|
0.92
|
84.57
|
27.89**
|
0.95
|
66.11
|
|
NADH
|
3.71
|
0.31
|
2.63**
|
0.28
|
70.89
|
1.95**
|
0.21
|
52.56
|
|
NADP
|
3.47
|
0.06
|
3.24**
|
0.05
|
93.37
|
2.42**
|
0.05
|
69.74
|
|
NADPH
|
2.87
|
0.12
|
2.25**
|
0.02
|
78.40
|
5.56**
|
0.22
|
193.73
|
- Direct measurement of NAD, NADH, NADP, and NADPH concentrations in S. aureus (in μg/ml and percentage of control value depending on the applied IQ-143 concentration). Statistically significant differences are indicated (*P < 0.05,**P < 0.01). SD, standard deviation.
