Figure 10
From: Improving RNA-Seq expression estimates by correcting for fragment bias
Correlation of GC content with measured bias. Panel a shows an example from human and panel b from yeast. Since the log fold change in effective length does not capture the full bias measurement for multiple isoform genes, the plots are limited to those with single isoforms. GC content appears to be correlated with our sequence bias measurements in some datasets, but not in others. GC content alone is not always a good proxy for fragment end bias.