Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum

Table 2 Candidate horizontal gene transfers from Bacteria

Pfam domain^a	Function in bacteria^b	D. discoideumdictyBase ID^c	Function in D. discoideum^c	D. purpureumprotein ID^d	D. purpureumdictyBase ID
Beta_elim_lyase	Aromatic amino acid lyase	DDB_G0281127	Unknown	154359	DPU_G0057350
BioY	Biotin metabolism	DDB_G0292424	Unknown	79107	DPU_G0053374
Cna_B	Unknown	DDB_G0292696	colA, Colossin A slug protein	96318	DPU_G0069302
Peroxidase	Dyp_peroxidase	DDB_G0273083	Unknown	35644	DPU_G0056076
Endotoxin_N	Insecticidal crystal protein	DDB_G0289249	Unknown	96621	DPU_G0058298
IPT	Isopentenyl transferase	DDB_G0277215	Discadenine production	92712	DPU_G0062048
IucA_IucC	Siderophore synthesis	DDB_G0294004	Unknown	No model^e	No model^e
OsmC	Osmoregulation	DDB_G0268884	Unknown	93234	DPU_G0070822
Peptidase S13	Dipeptidase/β-lactamase	DDB_G0271902	Penicillin-sensitive carboxypeptidase	6688	DPU_G0063426
PP_kinase	Polyphosphate synthesis	DDB_G0293524	Polyphosphate synthesis	45674	DPU_G0062710
TerD	Tellurium resistance	DDB_G0277501	capA/B	57536	DPU_G0062378
Thy1	Thymidylate synthesis	DDB_G0280045	thyA, thymidylate synthesis	149635	DPU_G0069806
DUF885	Unknown	DDB_G0278355	Unknown	155362	DPU_G0059974
DUF1121	Unknown	DDB_G0277411	Unknown	39626	DPU_G0062812
DUF1289	Unknown	DDB_G0282477	Unknown	27078	DPU_G0056950
DUF1294	Unknown	DDB_G0285825	Unknown	86664	DPU_G0067456

^aThe Pfam domain designation [99]. ^bConfirmed or proposed function of the prokaryotic ortholog is given. ^cThe D. discoideum gene ID number and functional annotation are from dictyBase [14]. ^dD. purpureum ortholog protein ID numbers [13]. All orthologs are 90 to 100% similar in amino acid sequence to the D. discoideum protein over >90% of their length. ^eA related sequence is present, but no protein model could be produced from the current assembly.

ISSN: 1474-760X