Figure 2

Arm switching frequency in the miRNA-seq data. (a) Arm-specific expression of at least 21 miRNAs varied between tissues. For all 10 tissues (points), log ratios of 5p to 3p arm expression for 21 miRNAs (blue lines) are plotted according to the arm on which dominant expression occurred, clearly illustrating differences between the tissues for each miRNA. (b) Sequence logo plots for hsa-miR-126 showing the switch between expression dominance from the 5p arm (placenta) to the 3p arm (heart, liver, and kidney). The pre-miRNA hairpin is displayed along the bottom.