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Table 1 Enrichment for Gene Ontology terms among hpl-2-regulated genes

From: Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism

Term

Count

P-value

Fold enrichment

Embryo down-regulated

   

   GO:0006396 - RNA processing

23

4.37E-05

2.7

   GO:0006796 - phosphate metabolic process

48

0.017

1.4

Embryo up-regulated

   

   GO:0006631 - fatty acid metabolic process

4

0.043

5

L3 down-regulated

   

   GO:0009712 - catechol metabolic process

5

3E-03

8.0

   GO:0043043 - peptide biosynthetic process

4

0.02

8.0

   GO:0046942 - carboxylic acid transport

5

3E-03

8.0

   GO:0006631 - fatty acid metabolic process

3

0.04

5.0

L3 up-regulated

   

   GO:0007126 - meiosis

15

3.21E-06

4.7

   GO:0022402 - cell cycle process

19

3.12E-05

3.1

   GO:0045132 - meiotic chromosome segregation

12

3.22E-05

4.0

  1. Gene Ontology (GO) terms are from the biological process ontology. GO information was downloaded from DAVID [110]. In some cases, more specific subtypes of the listed parental terms were also significantly enriched.