Evaluation of the performance of the three methods. (a) SpeCond (blue), TSGA (purple), propensity method (cyan). (b,c) Detailed parameter evaluation for the SpeCond and TSGA methods. (b) SpeCond: varying mlk (0 to 300) and rsd (0 to 2) parameters for the two steps with β = 6 and 0 and per = 0.1 and (0.2, 0.3, 0.5) for step 1 and step 2, respectively. The red line represents optimal parameter set for each false positive (FP) rate. (c) TSGA for the maximum number of specific tissue that can be detected N = 1, 2, 3, 4, 8, 11, 16, varying the H.critical value from 1 to 19.8. TP: true positive.