Table 6 Cytoskeletal proteins in Ich, T.thermophila and H. sapiens
Protein type | Ich | T. thermophila | H. sapiens |
|---|---|---|---|
Tubulins and modifying enzymes | |||
   α-Tubulin | 1 | 1 | 9 |
   α-Tubulin-like | 0 | 3 | 0 |
   β-Tubulin | 3 | 2 | 9 |
   β-Tubulin-like | 0 | 6 | 0 |
   γ-Tubulin | 1 | 1 | 2 |
   ε-Tubulin | 1 | 1 | 1 |
   δ-Tubulin | 0 | 1 | 1 |
   η-Tubulin | 1 | 1 | 0 |
   ι-Tubulin | 0 | 3 | 0 |
   Tubulin tyrosine ligase-like | 31 | 50 | 14 |
Motor proteins | |||
   Kinesin motor domain | 41 | 78 | 48 |
   Dynein heavy chain | 19 | 25 | 16 |
   Dynein intermediate chain | 6 | 6 | 7 |
   Dynein light intermediate chain | 1 | 2 | 3 |
   Dynein light chain | 16 | 14 | 9 |
   Myosin motor domain | 3 | 13 | 22 |
Centrins | Â | ||
   Centrin 1 | 1 | 1 | 1 |
   Centrin 2 | 2 | 1 | 1 |
   Centrin 3 | 1 | 1 | 1 |
   Centrin 4 | 1 | 1 | 0 |
Core basal body proteins (also includes centrins 2, 3; δ-, ε-tubulins) | |||
   Bld10/Cep135 | 1 | 1 | 1 |
   Centriolin | 0 | 1 | 1 |
   Cep76 | 0 | 0 | 1 |
   Cep164 | 0 | 1 | 1 |
   Dip13 | 0 | 0 | 2 |
   Poc1 | 1 | 1 | 2 |
   Poc5 | 1 | 1 | 1 |
   Sas4/CPAP | 2 | 1 | 2 |
   Sas6 | 1 | 2 | 1 |
   VFL1a/CLERC | 1 | 2 | 1 |
   WDR16 | 1 | 1 | 1 |
Ciliopathy associated proteins | |||
   MKS1 | 1 | 1 | 1 |
   MKS3 | 2 | 2 | 1 |
   MKS4/Cep290 | 0 | 0 | 1 |
   MKS5/RPGRIP1L | 1 | 1 | 1 |
   MKS6/CCD2A | 1 | 1 | 1 |
   AHI1 | 1 | 1 | 1 |
   NPHP1 | 1 | 1 | 1 |
   NPHP3 | 0 | 0 | 1 |
   NPHP4 | 1 | 1 | 1 |
   BBS1 | 1 | 1 | 2 |
   BBS2, 5, 7, 8, or 9 | 1 | 1 | 1 |
   BBS3/ARL6 | 0 | 1 | 1 |
   BBS4 | 0 | 1 | 1 |