|
Coverage
|
TP
|
TN
|
FP
|
FN
|
Accuracy
|
Sensitivity
|
Specificity
|
---|
St
|
0.21
|
134
|
44
|
40
|
13
|
0.77
|
0.91
|
0.52
|
Pfam
|
0.81
|
480
|
117
|
280
|
23
|
0.67
|
0.95
|
0.29
|
St U Pfam
|
0.87
|
490
|
145
|
291
|
35
|
0.66
|
0.93
|
0.33
|
St ∩ Pfam
|
0.15
|
124
|
16
|
29
|
1
|
0.82
|
0.99
|
0.36
|
- Coverage, accuracy, sensitivity and specificity of the different strategies and their combinations (U = union and ∩ = intersection) with respect to the negative dataset. Pfam, completeness of Pfam domains; St, structural plausibility. The definition of the other parameters is reported in Materials and methods. FN, false negative; FP, false positive; TN, true negative; TP, true positive.