Coding potential of the products of alternative splicing in human

Table 2 Results of the statistical analysis with respect to the negative dataset

	Coverage	TP	TN	FP	FN	Accuracy	Sensitivity	Specificity
St	0.21	134	44	40	13	0.77	0.91	0.52
Pfam	0.81	480	117	280	23	0.67	0.95	0.29
St U Pfam	0.87	490	145	291	35	0.66	0.93	0.33
St ∩ Pfam	0.15	124	16	29	1	0.82	0.99	0.36

Coverage, accuracy, sensitivity and specificity of the different strategies and their combinations (U = union and ∩ = intersection) with respect to the negative dataset. Pfam, completeness of Pfam domains; St, structural plausibility. The definition of the other parameters is reported in Materials and methods. FN, false negative; FP, false positive; TN, true negative; TP, true positive.