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Table 1 Results of the statistical analysis with respect to the unknown dataset

From: Coding potential of the products of alternative splicing in human

  Coverage TP TN FP FN Accuracy Sensitivity Specificity
AS 0.14 79 31 48 1 0.69 0.99 0.39
St 0.26 134 76 69 13 0.72 0.91 0.52
Pfam 0.81 480 165 227 23 0.72 0.95 0.41
AS U St 0.35 175 101 99 14 0.71 0.93 0.50
St U Pfam 0.89 490 203 257 35 0.71 0.93 0.44
AS U Pfam 0.85 485 186 250 24 0.71 0.95 0.43
AS U St U Pfam 0.92 494 221 272 36 0.70 0.93 0.45
AS ∩ St 0.06 38 6 18 0 0.71 1.00 0.25
St ∩ Pfam 0.18 124 38 39 1 0.80 0.99 0.49
AS ∩ Pfam 0.10 74 10 25 0 0.77 1.00 0.28
AS ∩ St ∩ Pfam 0.05 37 3 10 0 0.80 1.00 0.23
  1. Coverage, accuracy, sensitivity and specificity of the different strategies and their combinations (U = union and ∩ = intersection) with respect to the unknown dataset. AS, preservation of active sites; Pfam, completeness of Pfam domains; St, structural plausibility. The definition of the other parameters is reported in Materials and methods. FN, false negative; FP, false positive; TN, true negative; TP, true positive.