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Table 1 Motif occupancy classification performance using ES cell ChIP training data

From: Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis

Binding sites

All ES cell experiments

ES cell TF experiments

ES cell histone modifications

RAR (constitutively bound)

0.96

0.92

0.81

RAR (post-RA exclusively bound)

0.81

0.77

0.73

PPARγ (adipocytes)

0.62

0.58

0.53

Foxa2 (liver)

0.63

0.56

0.50

  1. Performance is measured as receiver operating characteristic (ROC) area under curves for SVMs trained to discriminate between significant binding sites and randomly selected unbound locations.