Figure 3From: Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesisConstitutive RAR binding without ES cell-poised Pol2 at Stra8 and Rarb. RAR is constitutively bound at these targets, but no enrichment of poised/initiating polymerase (Pol2-S5P) is observed in ES cells at these loci. Within 8 hours of retinoid exposure, the initiating and elongating forms of Pol2 are recruited to these genes.Back to article page