Figure 8

Analysis of a tumor sample with an unknown ploidy status and normal DNA contamination. A likelihood contour plot shows that there are three modes each corresponding to an alternative explanation of the SNP data: (a) the tumor has near-diploid karyotype and contaminated with 50% normal DNA content, (b) the tumor has a tetraploid karyotype with 60% normal DNA content and (c) the tumor has a near-triploid karyotype with negligible normal DNA content. The maximum log-likelihood at each mode is very similar.