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Table 3 Regions of high positive selection, in close proximity to genes, identified in the analysis of Williamson et al. [41]

From: Sequencing and analysis of an Irish human genome

Williamson et al. [41]regions of high positive selection

Corresponding regions of low Tajima's D in this analysis

Chr

Position (hg18)

Nearest gene

Position (hg18)

Nearest gene

Tajima's D

1

113519196

LRIG2 (50 kb)

113505001-113515000

-

-1.72

1

155990832

FCRL2 (0)

155990001-156000000

FCRL2 (0 kb)

-2.08

1

212654925

PTPN14 (0)

212595001-212605000

-

-1.09

2

140931201

LRP1B (0)

140930001-140940000

LRP1B (0 kb)

-2.06

2

201548002

MGC39518 (3 kb)

201455001-201465000

-

-1.73

3

29922879

RBMS3 (0)

29915001-29925000

RBMS3 (0 kb)

-2.17

3

43338322

SNRK (0)

43385001-43395000

-

-1.30

3

145075381

SLC9A9 (26 kb)

145090001-145100000

-

-1.71

4

71744283

IGJ (0)

71740001-71750000

IGJ (0 kb)

-2.55

4

169386385

FLJ20035 (0)

169395001-169405000

FLJ20035/DDX60 (0 kb)

-2.10

5

15527762

FBXL7 (26 kb)

15535001-15545000

FBXL7 (8.3 kb)

-2.23

6

128662923

PTPRK (0)

128655001-128665000

PTPRK (0 kb)

-2.37

8

57165523

RPS20 (16 kb)

57200001-57210000

PLAG1 (26 kb)

-2.06

10

45498260

ANUBL1 (10 kb)

45495001-45505000

FAM21C (0 kb)

-2.27

12

81525433

DKFZp762A217 (79 kb)

81520001-81530000

DKFZp762A217 (75 kb)

-2.21

13

37806830

UFM1 (15 kb)

37805001-37815000

-

-1.38

15

37639096

THBS1 (21 kb)

37640001-37650000

-

-1.95

15

89644996

SV2B (5 kb)

89640001-89650000

SV2B (0 kb)

-2.08

16

80605406

HSPC105 (3 kb)

80595001-80605000

-

-1.87

18

30388871

DTNA (0)

30380001-30390000

DTNA (0 kb)

-2.21

18

44274281

KIAA0427 (45 kb)

44365001-44375000

KIAA0427 (0 kb)

-2.28

  1. Regions in this analysis with a Tajima's D value of less than -2 within 100 kb of the corresponding region from Williamson et al. [41] are highlighted in bold. (Selection of 21 random positions in the genome 1,000 times never produced as many within close proximity to a window whose Tajima's D was less than -2.)