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Table 1 Attributes of each of the tiers

From: Genomic information infrastructure after the deluge

  Tier 1 Tier 2 Tier 3
Goal Explore and analyze new areas of biology Organize an appropriate area of biology Aggregate across all biology, provide information infrastructures
Main style of funding Response-mode and strategic grants for specific key datasets Strategic grants for an area of biology, with portions of response-mode grants for specific datasets Infrastructure funds, coupled to portions of strategic grants for specific biological areas
Time horizon of group Grant-driven, 3-5 years Strategic grant driven, 5-10 years Infrastructure driven, 10-20 years
Examples Many response-mode laboratories in universities and academic institutions Bioinformatics resource centers (BRCs), model organism databases EBI (Ensembl, Ensembl Genomes), NCBI (RefSeq)