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Figure 2 | Genome Biology

Figure 2

From: How do proteins gain new domains?

Figure 2

Hypothetical model of a multidomain protein gaining an intrinsically disordered region via a carboxy-terminal exon extension. This protein has three folded domains (based on Protein Data Bank entry 1BIB), colored yellow, blue and red, and a 40-residue disordered extension at its carboxyl terminus, colored green. The folded domains are shown as a surface representation, and the disordered region is shown as an ensemble model with multiple distinct structures representing its substantial conformational heterogeneity.

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