Chromosome analysis after ICSI with sperm from mice with NPYq deficiencies. (a) Fresh epididymal sperm from 9/10NPYq- male. (b) Fresh testicular sperm from 9/10NPYq- male. (c) Frozen testicular sperm from 9/10NPYq- male. (d) Frozen epididymal sperm from NPYq-2 male. (a) Paternal chromosome complement (m) with 19 normal chromosomes and 3 fragments (examples shown with arrowheads). (b) Normal paternal (m) and maternal (f) chromosome complements each showing 20 chromosomes. (c) Normal maternal complement (f, n = 20) and paternal karyoplate with 18 normal chromosomes and 6 chromosome fragments (examples shown with arrowheads). (d) Mormal maternal chromosomes (f, n = 20) and paternal (m) complement with multiple chromosome aberrations (>10 fragments; arrow). Scale bar = 10 μm.