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Figure 5 | Genome Biology

Figure 5

From: Deficiency in mouse Y chromosome long arm gene complement is associated with sperm DNA damage

Figure 5

Percentage of normal karyoplates after ICSI with sperm from mice with NPY deficiency. Sperm from males with severe NPYq deficiency (9/10NPYq- and NPYq-2) but not males with moderate NPYq gene loss (2/3NPYq) led to increased incidence of abnormal karyoplates compared to respective sperm types from their appropriate controls, as revealed by Fisher's exact probability test. Statistical significance: b = P < 0.01; d = P < 0.0001 versus matching sperm type in control. Two males were used per genotype; four sperm groups (epididymal, frozen epididymal, testicular and frozen testicular) were examined per male; approximately 15 (15.88 ± 6.52) oocytes were scored per group per male.

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