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Table 5 Clustering of GBM-related altered genes occurring in two or more samples in the FI network

From: A human functional protein interaction network and its application to cancer data analysis

Data set

Cancer genes

Genes in FI network (%)

Genes in cluster

Percentage of genes in cluster (P-value via random permutation)

TCGA

164

98 (60%)

71

72% (<0.001)

Parsons

111

65 (59%)

46

71% (<0.001)

  1. The numbers in the 'Cancer genes' column are for altered genes in two or more samples from the TCGA and Parsons data sets. Genes were collected using both somatic mutations and CNVs.