GWASs and the age of human as the model organism for autoimmune genetic research

Table 1 Loci associated with multiple autoimmune diseases

Chromosome	Position	Gene(s)	Disease*	References
1	67466790	IL23R	Psoriasis, CD, UC	[7, 12, 53]
1	114179091	PTPN22	SLE, CD, RA, T1D	[7, 8, 54, 55]
1	116905738	CD58	MS, RA	[5, 11]
1	205006527	IL10	SLE, T1D, UC	[6, 8, 14]
2	102437000	IL18RAP	T1D, celiac	[9]
2	191672878	STAT4	RA, SLE	[56]
2	204402121	CTLA4	RA, T1D, celiac	[6, 13, 57]
4	25694609	RBPJ	T1D, RA	[6]
4	123351942	IL2	T1D, Celiac, RA, UC	[6, 25, 58]
5	150437678	TNIP1	SLE, psoriasis	[8]
5	158650367	IL12B	Psoriasis, CD	[7, 12]
6	106541962	PRDM1, ATG5	CD, RA, SLE	[5, 7, 8]
6	138014761	TNFAIP3	Celiac, RA, SLE, psoriasis	[12, 13, 59–61]
6	159385965	TAGAP	Celiac, RA	[5, 10]
6	167357978	CCR6	CD, RA	[7]
7	128376236	IRF5	SLE, RA	[31, 62]
8	11377591	BLK	SLE, RA	[35, 63]
10	6138955	IL2RA	RA, MS, T1D	[6, 64]
10	6430456	PRKCQ	T1D, RA	[4, 65]
16	11074189	CLEC16A	MS, T1D	[11, 66]
18	12769947	PTPN2	CD, celiac, T1D	[7, 13, 66]

*CD, Crohn's disease; MS, multiple sclerosis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; T1D, type 1 diabetes; UC, ulcerative colitis.

ISSN: 1474-760X