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Table 1 Gene Ontology categories ranked in the top 25 in the standard method but not in length bias adjusted GOseq

From: Gene ontology analysis for RNA-seq: accounting for selection bias

GOID

Term

Ontology

Rank standard

Rank GOseq

Average gene length in category

GO:0005622

Intracellular

CC

9

38

2,710

GO:0005524

ATP binding

MF

12

113

3,133

GO:0008270

Zinc ion binding

MF

13

145

2,817

GO:0016020

Membrane

CC

16

702

2,571

GO:0046872

Metal ion binding

MF

17

255

2,734

GO:0006355

Regulation of transcription, DNA-dependent

BP

19

266

2,752

GO:0000139

Golgi membrane

CC

22

28

2,855

GO:0016740

Transferase activity

MF

25

116

2,721

  1. The median gene length of all categories are significantly longer than average using a Mann-Whitney test. BP, biological process; CC, cellular component; MF, molecular function.