Table 3 Significant probe sets identified by comparison of reciprocal congenic strains
| Â | Â | Â | Ratio of expression (iP vs P.NP and NP.P vs iNP)a | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Amygdala | Nucleus accumbens | Frontal cortex | Hippocampus | Caudate putamen | Combined regions | ||||||
Probe set | Symbol | Gene title | iP vs. P.NP | NP.P vs. iNP | iP vs. P.NP | NP.P vs. iNP | iP vs. P.NP | NP.P vs. iNP | iP vs. P.NP | NP.P vs. iNP | iP vs. P.NP | NP.P vs. iNP | iP vs. P.NP | NP.P vs. iNP |
1399134_at | LOC500054 | similar to POT1-like telomere end-binding protein | -1.13 | -1.11 | -1.13 | -1.11 | -1.07 | -1.18 | -1.13 | -1.22 | -1.06 | -1.07 | -1.10 | -1.14 |
1386777_at | LOC500054 | similar to POT1-like telomere end-binding protein | -1.04 | -1.13 | -1.10 | -1.35 | -1.10 | -1.21 | -1.19 | -1.29 | -1.05 | -1.11 | -1.10 | -1.21 |
1382865_at | Tsga14 | testis specific gene A14 | -1.06 | -1.09 | -1.13 | -1.06 | -1.05 | -1.06 | -1.11 | -1.10 | -1.00 | -1.14 | -1.07 | -1.09 |
1382409_at | Tsga14 | testis specific gene A14 | -1.06 | -1.12 | -1.06 | -1.16 | -1.09 | -1.02 | -1.04 | -1.08 | -1.09 | -1.01 | -1.07 | -1.08 |
1383828_at | Tsga13 | EST-testis specific gene A13 (predicted) | -1.25 | -1.32 | -1.45 | -1.25 | -1.19 | -1.26 | -1.57 | -1.21 | -1.26 | -1.13 | -1.34 | -1.23 |
1369895_s_at | Podxl | podocalyxin-like | 1.04 | -1.01 | 1.00 | 1.15 | 1.05 | 1.01 | 1.04 | 1.08 | 1.03 | 1.06 | 1.03 | 1.06 |
1378956_at | --- | EST-similar to plexin A4 | 1.55 | ND | 2.16 | ND | 1.73 | 1.55 | 1.95 | 1.39 | 2.28 | ND | 1.91 | 1.41 |
1389291_at | Chchd3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | -1.09 | -1.10 | -1.06 | -1.13 | -1.06 | -1.15 | -1.11 | -1.10 | -1.05 | -1.16 | -1.08 | -1.13 |
1378824_at | --- | EST-4.8 Kb at 3' side of similar to solute carrier family 35, member B4 | 1.06 | 1.08 | 1.09 | ND | 1.10 | 1.08 | 1.03 | 1.04 | 1.09 | ND | 1.07 | 1.10 |
1367734_at | Akr1b1 | aldo-keto reductase family 1, member B1 | 1.12 | 1.12 | 1.22 | 1.13 | 1.27 | 1.29 | 1.16 | 1.11 | 1.25 | 1.24 | 1.20 | 1.18 |
1395190_at | Akr1b10 | aldo-keto reductase family 1, member B10 | 1.28 | 1.12 | 1.55 | 1.27 | 1.21 | 1.21 | 1.34 | 1.05 | 1.23 | 1.38 | 1.32 | 1.20 |
1382034_at | Akr1b10 | aldo-keto reductase family 1, member B10 | 1.19 | -1.02 | -1.41 | -1.08 | 1.09 | -1.16 | -1.17 | -1.05 | 1.12 | 1.12 | -1.02 | -1.04 |
1383551_at | Bpgm | 2,3-bisphosphoglycerate mutase | 1.12 | 1.10 | 1.14 | -1.07 | 1.13 | 1.16 | 1.14 | 1.15 | 1.10 | 1.10 | 1.13 | 1.09 |
1388544_at | Bpgm | 2,3-bisphosphoglycerate mutase | 1.09 | 1.08 | 1.10 | 1.11 | 1.11 | 1.14 | 1.10 | 1.13 | 1.08 | 1.06 | 1.10 | 1.10 |
1390042_at | Tmem140 | transmembrane protein 140 | 1.21 | 1.32 | 1.38 | 1.24 | 1.14 | 1.13 | 1.11 | 1.14 | 1.27 | 1.06 | 1.22 | 1.18 |
1383598_at | Wdr91 | WD repeat domain 91 (Wdr91) | 1.33 | 1.34 | 1.30 | ND | 1.47 | 1.27 | 1.50 | 1.23 | 1.46 | 1.26 | 1.41 | 1.25 |
1378125_at | --- | EST-0.5 Kb at 3' side of similar to HSPC049 protein | 1.32 | 1.28 | 1.46 | 1.22 | 1.35 | 1.32 | 1.42 | 1.24 | 1.42 | 1.31 | 1.40 | 1.27 |
1373746_at | Wdr91 | WD repeat domain 91 | -1.21 | -1.09 | -1.30 | -1.14 | -1.20 | -1.13 | -1.26 | -1.14 | -1.18 | -1.23 | -1.23 | -1.14 |
1373190_at | Cnot4 | CCR4-NOT transcription complex, subunit 4 | 1.00 | 1.09 | 1.02 | 1.16 | 1.02 | 1.01 | 1.07 | 1.14 | 1.03 | 1.00 | 1.03 | 1.08 |
1388441_at | LOC689574 | hypothetical protein LOC689574 | -1.10 | -1.03 | 1.02 | -1.06 | -1.05 | -1.13 | -1.08 | -1.10 | -1.04 | -1.09 | -1.05 | -1.08 |
1377890_at | --- | EST-4.9 Kb at 3' side of solute carrier family 13, member 4 | 1.17 | 1.50 | 1.22 | 1.34 | 1.16 | 1.30 | 1.14 | 1.23 | 1.19 | 1.19 | 1.18 | 1.31 |
1392510_at | Fam180a | family with sequence similarity 180, member A | 1.22 | 1.49 | 1.78 | 1.43 | 1.13 | 1.08 | 1.15 | 1.24 | 1.08 | 1.11 | 1.25 | 1.26 |
1391721_at | --- | EST-2.5 Kb at 5' side of cholinergic receptor, muscarinic 2 | -1.55 | ND | -2.91 | ND | -1.82 | -2.10 | -1.71 | -1.63 | -1.88 | ND | -1.92 | -1.67 |
1379480_at | Dgki | diacylglycerol kinase, iota | 1.13 | 1.14 | 1.23 | 1.22 | 1.17 | 1.24 | 1.26 | 1.09 | 1.25 | 1.27 | 1.21 | 1.19 |
1395107_at | Dgki | EST-similar to diacylglycerol kinase iota | -1.02 | 1.04 | -1.15 | 1.06 | 1.01 | -1.01 | 1.10 | 1.16 | -1.01 | 1.02 | -1.01 | 1.05 |
1393410_at | --- | EST-0.79 Kb at 5' side of similar to contactin associated protein-like 2 isoform a | 1.00 | -1.18 | 1.09 | 1.15 | -1.09 | -1.11 | 1.02 | -1.06 | 1.03 | 1.00 | 1.01 | -1.04 |
1390393_at | --- | EST-5 Kb at 5' side of similar to contactin associated protein-like 2 isoform a | -1.08 | -1.15 | -1.01 | 1.01 | -1.16 | -1.21 | -1.03 | -1.12 | -1.03 | -1.07 | -1.06 | -1.11 |
1370007_at | Pdia4 | protein disulfide isomerase associated 4 | 1.34 | 1.24 | 1.24 | 1.10 | 1.14 | 1.19 | 1.06 | 1.12 | 1.36 | 1.14 | 1.22 | 1.16 |
1397447_at | Zfp398 | zinc finger protein 398 | -1.04 | -1.13 | -1.08 | -1.08 | -1.04 | 1.01 | -1.04 | -1.02 | -1.06 | 1.01 | -1.05 | -1.04 |
1380094_a_at | Zfp212 | zinc finger protein 212 | 1.22 | ND | 1.30 | ND | 1.21 | ND | 1.28 | 1.15 | 1.43 | ND | 1.29 | 1.16 |
1390625_at | RGD1304879 | similar to zinc finger protein 398 (zinc finger DNA binding protein p52/p71) | 1.43 | 1.40 | 1.27 | 1.39 | 1.33 | 1.20 | 1.30 | 1.36 | 1.46 | 1.22 | 1.36 | 1.31 |
1377600_at | Znf777 | zinc finger protein 777 | 1.08 | 1.10 | 1.07 | -1.00 | 1.09 | 1.12 | 1.13 | 1.08 | 1.03 | 1.10 | 1.08 | 1.08 |
1375914_at | Krba1 | KRAB-A domain containing 1 | -1.04 | -1.07 | -1.07 | 1.04 | -1.07 | -1.02 | -1.05 | -1.14 | -1.06 | -1.12 | -1.06 | -1.06 |
1371691_at | Rarres2 | retinoic acid receptor responder (tazarotene induced) 2 | -1.14 | -1.01 | 1.12 | -1.09 | -1.16 | -1.22 | -1.23 | -1.19 | -1.01 | -1.08 | -1.08 | -1.11 |
1376401_at | RGD1561107 | EST-replication initiator 1 | 1.12 | 1.10 | 1.16 | 1.13 | 1.19 | 1.12 | 1.13 | 1.13 | 1.18 | 1.14 | 1.15 | 1.12 |
1382755_at | Tra2a | rranscribed locus | 1.11 | 1.16 | -1.13 | -1.12 | 1.07 | 1.20 | 1.13 | 1.32 | 1.11 | 1.43 | 1.06 | 1.19 |
1387154_at | Npy | neuropeptide Y | -1.04 | -1.19 | -1.06 | 1.12 | -1.11 | -1.11 | -1.09 | -1.14 | -1.08 | -1.05 | -1.08 | -1.07 |
1380062_at | Mpp6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) | 1.02 | 1.00 | 1.03 | -1.09 | 1.07 | 1.04 | 1.13 | 1.19 | 1.06 | 1.02 | 1.06 | 1.03 |
1383324_at | Mpp6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) | 1.01 | 1.09 | 1.10 | -1.01 | 1.11 | 1.12 | 1.10 | 1.20 | 1.06 | 1.09 | 1.07 | 1.10 |
1397419_at | Mpp6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) | -1.02 | 1.12 | 1.12 | 1.01 | 1.18 | 1.13 | 1.14 | 1.22 | 1.07 | 1.10 | 1.09 | 1.11 |
1397949_at | --- | EST-similar to MAGUK p55 subfamily member 6 | -1.00 | 1.13 | 1.16 | 1.06 | 1.15 | 1.18 | 1.15 | 1.20 | 1.07 | 1.12 | 1.10 | 1.14 |
1398627_at | --- | EST- similar to MAGUK p55 subfamily member 6 | -1.01 | 1.04 | 1.05 | 1.10 | 1.09 | 1.09 | 1.07 | 1.16 | 1.04 | 1.02 | 1.05 | 1.08 |
1384136_at | Osbpl3 | oxysterol binding protein-like 3 | -1.06 | -1.03 | -1.09 | 1.07 | -1.15 | -1.03 | -1.12 | -1.16 | -1.15 | -1.06 | -1.11 | -1.04 |
1378543_at | Hnrnpa2b1 | EST-heterogeneous nuclear ribonucleoprotein A2/B1 (predicted) | -1.31 | -1.23 | -1.26 | -1.18 | -1.17 | -1.35 | -1.16 | -1.16 | -1.19 | -1.25 | -1.22 | -1.23 |
1371395_at | Cbx3 | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | -1.07 | -1.07 | -1.04 | -1.00 | -1.04 | -1.02 | -1.03 | -1.03 | -1.05 | -1.10 | -1.04 | -1.04 |
1379275_at | Snx10 | sorting nexin 10 | 2.18 | 1.40 | 1.67 | -1.05 | 1.94 | 1.58 | 1.69 | 1.58 | 2.02 | 1.55 | 1.89 | 1.39 |
1383585_s_at | Snx10 | EST-sorting nexin 10 | -1.10 | -1.17 | -1.08 | -1.05 | -1.12 | -1.09 | -1.06 | -1.03 | -1.08 | -1.26 | -1.09 | -1.12 |
1377198_at | --- | EST-2 Kb at 3' side of src family associated phosphoprotein 2 | -1.23 | -1.33 | -1.16 | -1.09 | -1.10 | -1.09 | -1.10 | -1.19 | -1.03 | -1.15 | -1.12 | -1.17 |
1369979_at | Skap2 | src family associated phosphoprotein 2 | -1.20 | -1.22 | -1.11 | -1.04 | -1.03 | -1.16 | -1.05 | -1.07 | 1.01 | -1.12 | -1.07 | -1.12 |
1388118_at | Hibadh | 3-hydroxyisobutyrate dehydrogenase | -1.07 | -1.01 | -1.01 | -1.04 | -1.05 | -1.09 | -1.05 | -1.03 | -1.06 | -1.05 | -1.05 | -1.04 |
1378742_at | LOC682099 | EST-similar to juxtaposed with another zinc finger protein 1 | 2.05 | 1.64 | 1.92 | 1.80 | 2.11 | 1.71 | 1.85 | 1.76 | 1.83 | 1.43 | 1.95 | 1.66 |
1379629_at | --- | EST-4.7 kb at 5' side of similar to cAMP responsive element binding protein 5 isoform alpha | -1.38 | -1.35 | -1.40 | -1.37 | -1.34 | -1.27 | -1.42 | -1.20 | -1.41 | -1.34 | -1.39 | -1.30 |
1394833_at | --- | EST-0.6 Kb at 5' side of beta chimerin | -1.12 | -1.15 | -1.04 | -1.19 | -1.08 | 1.02 | -1.06 | -1.10 | 1.08 | -1.03 | -1.04 | -1.09 |
1370648_a_at | Wipf3 | WAS/WASL interacting protein family, member 3 | 1.01 | 1.18 | -1.01 | 1.00 | -1.01 | 1.09 | 1.00 | -1.10 | 1.11 | 1.12 | 1.02 | 1.06 |
1392541_at | Ggct | gamma-glutamyl cyclotransferase | -1.34 | -1.19 | -1.28 | -1.06 | -1.26 | -1.26 | -1.18 | -1.08 | -1.33 | -1.26 | -1.28 | -1.16 |
1398107_at | Ggct | gamma-glutamyl cyclotransferase | -1.10 | -1.15 | -1.02 | 1.14 | -1.17 | ND | -1.06 | -1.07 | -1.15 | -1.00 | -1.10 | -1.03 |
1394973_at | Pde1c | EST-cyclic nucleotide phosphodiesterase 1 C | 1.14 | -1.01 | 1.08 | 1.09 | 1.02 | 1.02 | -1.02 | -1.01 | 1.37 | 1.16 | 1.11 | 1.05 |
1375640_at | Fkbp9 | FK506 binding protein 9 | -1.05 | 1.28 | 1.23 | 1.01 | 1.15 | 1.04 | 1.02 | 1.01 | 1.07 | 1.05 | 1.08 | 1.07 |
1388493_at | Ecop | EGFR-coamplified and overexpressed protein | -1.05 | -1.10 | -1.04 | -1.00 | -1.10 | -1.09 | -1.05 | -1.05 | -1.11 | -1.09 | -1.07 | -1.06 |
1396215_at | --- | EST-similar to RIKEN cDNA 2610022G08 | 1.01 | -1.07 | -1.07 | -1.10 | -1.03 | -1.07 | -1.08 | -1.07 | -1.14 | -1.20 | -1.06 | -1.10 |
1394939_at | Ppm1k | protein phosphatase 1 K (PP2C domain containing) | -1.74 | -2.67 | -2.05 | -2.36 | -2.79 | -2.57 | -1.86 | -2.05 | -2.39 | -2.05 | -2.13 | -2.33 |
1392921_at | Ppm1k | Protein phosphatase 1 K (PP2C domain containing) | -1.07 | -1.22 | -1.21 | -1.19 | -1.12 | -1.16 | -1.14 | -1.22 | -1.15 | -1.12 | -1.14 | -1.18 |
1388778_at | --- | EST-3.6 Kb at 5' side of similar to protein phosphatase 1 K (PP2C domain containing) | -1.27 | -1.27 | -1.27 | -1.17 | -1.18 | -1.27 | -1.22 | -1.23 | -1.22 | -1.26 | -1.23 | -1.24 |
1367977_at | Snca | synuclein, alpha | 1.03 | -1.08 | -1.04 | -1.11 | -1.10 | -1.09 | 1.07 | 1.03 | -1.12 | -1.12 | -1.03 | -1.07 |
1385271_at | RGD1565731 | EST-similar to KIAA1680 protein (predicted) | -1.02 | 1.04 | -1.05 | -1.08 | -1.03 | -1.02 | -1.20 | -1.11 | -1.09 | -1.01 | -1.08 | -1.04 |
1391945_at | --- | Transcribed locus | 2.01 | 1.33 | 2.37 | 1.60 | 1.54 | 1.38 | 1.88 | 1.30 | 2.61 | 1.70 | 2.05 | 1.45 |
1393607_at | Grid2 | EST-glutamate receptor, ionotropic, delta 2 | -1.27 | -1.34 | -1.13 | 1.04 | -1.17 | -1.14 | -1.12 | -1.23 | -1.02 | -1.08 | -1.14 | -1.14 |
1386869_at | Actg2 | actin, gamma 2, smooth muscle, enteric | 1.03 | 1.05 | 1.07 | -1.11 | 1.03 | -1.00 | -1.06 | -1.10 | -1.01 | -1.02 | 1.01 | -1.03 |
1379610_at | --- | EST | 1.19 | 1.31 | -1.00 | ND | 1.14 | 1.03 | 1.24 | 1.07 | -1.03 | ND | 1.10 | 1.06 |
1376481_at | Adamts9 | a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 | 1.09 | 1.30 | 1.16 | ND | 1.22 | ND | 1.30 | 1.28 | 1.27 | ND | 1.20 | 1.18 |
1376747_at | --- | EST, strongly similar to membrane associated guanylate kinase, WW and PDZ domain containing 1 isoform b [Mus musculus] | -1.11 | -1.22 | 1.00 | 1.05 | -1.25 | -1.12 | 1.06 | 1.02 | -1.20 | -1.13 | -1.09 | -1.08 |
1381871_at | NA | Transcribed locus | 1.21 | 1.20 | -1.05 | 1.90 | 1.28 | 1.49 | 1.31 | 1.42 | 1.19 | 1.08 | 1.18 | 1.39 |
1384504_at | Magi1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | 1.15 | 1.05 | 1.05 | 1.41 | 1.16 | 1.20 | 1.20 | 1.08 | 1.08 | 1.17 | 1.13 | 1.17 |
1397438_at | Magi1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | 1.26 | 1.01 | 1.12 | 1.09 | ND | 1.02 | 1.26 | ND | 1.17 | 1.08 | 1.18 | 1.04 |