Figure 8

Nuclear membrane association pattern of an X;IV fusion chromosome. (a) Schematic representation of the wild-type (N2 strain) chromosomes X and IV, and the X;IV fusion chromosome mnT12. Large LEM-2 domains are indicated in dark colors. The arrow indicates the fusion point. (b) LEM-2 ChIP-chip signals on chromosomes X and IV in wild type (red, top) and on the X;IV fusion chromosome (black, bottom). Wild-type data are the average of four biological replicates. Data from the fusion strain are the average of two biological replicates. The arrow indicates the fusion point. The boxes indicate the regions shown more closely in (c-f). (c-f) LEM-2 ChIP-chip signal patterns in wild type (red) or the fusion chromosome strain (black) at the ends of chromosome X (c,d) or chromosome IV (e,f).