Table 4 Metabolic pathways that are affected in zebrafish liver cancer with P-value < 0.05
MetaFishNet pathway | Selected enzymes | Enzymes in pathway | P-value |
|---|---|---|---|
ROS detoxification | 2 | 2 | 0.002 |
3-Chloroacrylic acid degradation | 2 | 2 | 0.002 |
Tyrosine metabolism | 8 | 55 | 0.002 |
Xenobiotics metabolism | 3 | 8 | 0.004 |
Glycolysis and Gluconeogenesis | 6 | 44 | 0.013 |
Fatty acid metabolism | 3 | 13 | 0.019 |
Butanoate metabolism | 3 | 14 | 0.023 |
Leukotriene metabolism | 3 | 17 | 0.040 |
Tryptophan metabolism | 4 | 29 | 0.040 |
Ascorbate (vitamin C) and aldarate metabolism | 1 | 1 | 0.046 |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | 1 | 1 | 0.046 |