Metabolic enzymes in common between human and fish. Among the 1,430 human enzymes compfiled from ExPASy and BRENDA  databases, 1,131 are included in the human metabolic models (shaded in light blue). Among the 911 enzymes found in fish genomes, 705 are included in MetaFishNet reactions (shaded in salmon). In the models, 632 enzymes are shared between human and fish. The disparity of numbers reflects that human enzymes are better annotated than fish. Please note that isozymes are not distinguished here.