Figure 3

Increased variation in body weight in Trim28^MommeD9/+ mice. (a) Twenty Trim28^+/+ mice and 33 Trim28^MommeD9/+ mice (all female) were weighed between 3 and 40 weeks of age. The data are the sum of 170 data points representing 103 Trim28^MommeD9/+ and 67 Trim28^+/+ body weight measurements. Trim28^MommeD9/+ mice appear to have a greater variation in weight as they age. (b) There is no correlation between age and weight between 20 and 40 weeks of age in 15 Trim28^+/+ mice and 25 Trim28^MommeD9/+ mice; however, Trim28^MommeD9/+ mice are heavier on average (P = 0.008). (c) Trim28^MommeD9/+ mice have a significant increase in weight variation between the ages of 20 and 40 weeks (P = 0.005).