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Table 2 Average performance of LDsplit on simulation data

From: Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome

Condition

Correct prediction of hot/cold alleles (%)

Sensitivity (%)

Specificity (%)

Positive predictive value (%)

Normal

89.26 ± 18.23

63.15 ± 26.42

58.71 ± 26.53

46.29 ± 22.22

Recurrent mutation

93 ± 9.88

70 ± 27.16

51.78 ± 21.99

43.58 ± 22.49

Long BGC tract (10 kb)

84.29 ± 22.77

53.4 ± 28.34

75.65 ± 12.94

52.60 ± 25.27

  1. The standard deviations are slightly high because we sampled only ten sets of haplotypes for each parameter configuration due to the high computational cost of LDsplit.