Table 1 Effect of removing outliers in the case study of the DNA2 hotspot and FG11 SNP
From: Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome
Before removal of outliers | After removal of outliers | |||||
|---|---|---|---|---|---|---|
Population | Outlier chromosome | Grubbs P-value for outlier | Shapiro P-value (normality of Δρ) | Association P-value for FG11 | Shapiro P-value (normality of Δρ) | Association P-value for FG11 |
CHB + JPT | 29 | 6.6e-7 | 0.00193 | 0.006258 | 0.5014 | 0.0004474 |
32 | 6.9e-6 | |||||
56 | 0.051 | |||||
CEU | 102 | 0.00111 | 0.003336 | 0.08024 | 0.3915 | 0.2129 |
YRI | 116 | 0.03 | 0.04887 | 0.1884 | 0.1302 | 0.02349 |
52 | 0.028 | |||||