Skip to main content

Table 1 Overview of mouse tumors analyzed

From: Somatic structural rearrangements in genetically engineered mouse mammary tumors

Number of samples

Genotype

Latency (days)

Homologous repair

p53 status

Reference

Identifiers

Histology

Tumor (%)

2

K14cre;Trp53 flox/flox

504

Proficient

Heterozygous

Jonkers et al. 2001 [20]

PD3685a

Mesenchymal

75

  

386

   

PD3686a

Mesenchymal

50

2

K14cre;Cdh1 flox/flox ;Trp53 flox/flox

449

Proficient

Null

Derksen et al. 2006 [19]

PD3679a

mILCa

85

  

328

   

PD3680a

mILCa/Carcinoma

85

2

K14cre;Brca1 flox/flox ;Trp53 flox/flox

99

Deficient

Null

Liu et al. 2007 [21]

PD3681a

Carcinoma

95

  

247

   

PD3682a

Carcinoma

95

2

K14cre;Brca2 flox/flox ;Trp53 flox/flox

144

Deficient

Null

Jonkers et al. 2001 [20]

PD3683a

Carcinoma

95

  

227

   

PD3684a

Carcinoma

95

  1. aMouse invasive lobular carcinoma.