Figure 5

Human cell lines frequently carry homozygous deletions of the LRP1B gene. (a) Pie chart showing the proportion of the 770 cell lines containing homozygous deletions in the LRP1B gene. (b) Heatmap showing which exons of the LRP1B gene have been homozygously deleted. The x-axis shows the exons in transcriptional order. The y-axis shows the different cell lines, clustered using hierarchical Euclidean clustering on the deletion patterns. The color bar along the y-axis shows whether an in-frame transcript would remain if these exons have been deleted.