Figure 1

Overview of somatic rearrangements in mouse mammary tumors. (a) Homologous recombination deficient tumors. (b) Homologous recombination proficient tumors. Circos plots showing the genome-wide distribution of structural aberrations. An ideogram of the mouse genome is show in the outer ring. The blue line indicates changes in copy number as determined by read coverage density. Intra- (green) and inter-chromosomal (purple) rearrangements are shown by lines within the circle. The bar plots show the absolute number of rearrangements found per type. Dark blue denotes deletions, red denotes tandem duplications, green denotes inversions, light blue denotes interchromosomal rearrangements, and orange denotes amplifications.