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Table 1 Immune signaling pathway statistics

From: NetPath: a public resource of curated signal transduction pathways

  Pathway Molecular association events Catalysis events Transport events Total reactions Number of upregulated genes annotated Number of downregulated genes annotated Number of PubMed links
1 T cell receptor 202 215 13 430 453 178 1,153
2 B cell receptor 172 136 43 351 253 182 990
3 IL-1 55 44 9 108 161 79 461
4 IL-2 68 76 11 155 539 301 1289
5 IL-3 65 52 5 122 43 10 250
6 IL-4 59 47 5 111 222 90 519
7 IL-5 26 40 6 72 167 9 308
8 IL-6 65 58 7 130 84 25 332
9 IL-7 14 39 2 55 57 14 175
10 IL-9 14 20 4 38 25 1 103
Total 10 740 727 105 1,572 2,004 889 5,580