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Table 4 Average incoming connectivity for the Gene Ontology pathways from all levels in A. thaliana

From: Reverse-engineering the Arabidopsis thaliana transcriptional network under changing environmental conditions

GO pathways* Number of genes Number of TFs Number of TF/Number of genes Number of FFLs§
Top five with the highest total number of TFs     
   Response to other organisms 296 2,249 7.6 9,865
   Secondary metabolic process 284 1,964 6.9 3,321
   Response to temperature stimulus 238 1,650 6.9 10,151
   Anatomical structure morphogenesis 291 1,537 5.3 13,275
   Response to radiation 250 1,524 6.1 6,233
Top five with the lowest total number of TFs     
   Glycerophospholipid metabolic process 21 38 1.8 69
   Sulfur amino acid biosynthetic process 24 60 2.5 13
   Gametophyte development 24 62 2.6 1
   Cellular morphogenesis in differentiation 25 68 2.7 78
   Indole and derivative metabolic process 22 71 3.2 46
Top five with the highest relative number of TFs     
   Defense response to fungus 26 355 13.7 4,353
   Photosynthesis 80 1,064 13.3 2,459
   Response to light intensity 26 334 12.8 2,652
   Chlorophyll biosynthetic process 22 243 11.0 443
   Porphyrin biosynthetic process 39 421 10.8 754
Top five with the lowest relative number of TFs     
   Glycerophospolipic metabolic process 21 38 1.8 0
   Membrane lipid biosynthetic process 48 111 2.3 121
   Sulfur compound biosynthetic process 32 75 2.3 98
   Golgi vesicle transport 44 104 2.4 47
   Biogenic amine metabolic process 32 76 2.4 53
  1. *Only GO pathways involving more than 20 genes and less than 300 from all levels were selected. Total number of TFs that regulate the genes of the GO pathway. Relative number of TFs. §Total number of FFLs involved in the GO pathway.