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Table 5 Functional properties of newly described RRG genes

From: Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae

 

Systematic name

Mitochondrial localization

Δmip1mating

Cytoduction

Nucleoids after cytoduction

Translation activity after cytoduction

RRG1

YDR065w

[34]

-

-

Altered

Absent

RRG2

YGR150c

[34, 35]

-

-

Altered

Absent

RRG3 (AIM22)

YJL046w

[69]

+

-

WT

WT

RRG4 (IRC19)

YLL033w

Unknown

-

-

WT

WT

RRG5 (GEP5)

YLR091w

[6, 34, 35]

-

-

Absent

Absent

RRG6 (HER2)

YMR293c

[6, 34, 35]

-

-

Altered

Absent

RRG7

YOR305w

[35]

+

+

ND

ND

RRG8

YPR116w

[35]

-

-

Altered

Absent

RRG9

YNL213c

[34]

-

-

Altered

WT

RRG10

YJL062w-a

[34, 35]

+

-

WT

Altered

  1. References refer to published evidence of mitochondrial localization of Rrg proteins; + indicates rescue by mating with Δmip1 or cytoduction, respectively. WT, wild type-like; ND, not determined. See text for details.