Class | Respiration after mating with Δmip1 | Respiration after cytoduction | Associated gene functions |
---|---|---|---|
I | - | - | Genes essential for maintenance of mtDNA (16 mutants); or genes essential for respiration with gradual loss of mtDNA (102 mutants) |
II | + | + | Additional effects of extra-genomic factors and/or acquired mitochondrial damage (23 mutants) |
III | + | - | Genes essential for respiration but not for maintenance of mtDNA (134 mutants) |
IV | - | + | Genes dispensable for respiration, gradual loss of mtDNA (44 mutants) |