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Figure 6 | Genome Biology

Figure 6

From: Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection

Figure 6

N-BP-induced accumulation of unprenylated Rap1A and increase of DBF4, but not of TBCB, can be reversed by GGPP. Western blot (WB) analysis of MCF-7 cells treated with 10-4 M ALE alone or in combination with 25 μM GGPP. The same volume of absolute ethanol was used as control vehicle of GGPP (Ctrl). Actin was used to show equal loading of the lanes.

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Genome Biology

ISSN: 1474-760X

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