Table 1 List of candidates
From: A global survey identifies novel upstream components of the Ath5 neurogenic network
Name | Fold-change | ID |
|---|---|---|
Group 1: repressors in RPCs | Â | Â |
   AATF | 0.21 ± 0.02 | Rb-binding protein Che-1 |
   ARG1 | 0.27 ± 0.02 | Liver-type arginase |
   ATP-synthase | 0.28 ± 0.04 | ATP synthase beta chain |
   Cnot10 | 0.15 ± 0.01 | CCR4-NOT transcription complex, subunit 10 |
   DuS4L | 0.28 ± 0.01 | tRNA-dihydrouridine synthase 4-like |
   KPNA4 | 0.25 ± 0.04 | Importin alpha-4 subunit |
   MCM2 | 0.27 ± 0.00 | DNA replication licensing factor 2 |
   USP25 | 0.28 ± 0.05 | Ubiquitin carboxyl-terminal hydrolase 25 |
   WDR43 | 0.29 ± 0.04 | WD repeat protein 43, unknown function |
Group 2: activators in RPCs | Â | Â |
   Bcat2 | 2.93 ± 0.27 | Mitochondrial branched chain aminotransferase 2 |
   Cbx7 | 2.96 ± 0.14 | Polycomb group gene |
   CEB55 | 4.70 ± 0.39 | Centrosomal protein of 55 kDa |
   GPI deacetylase | 15.00 ± 0.81 | Vesicular transport |
   PTPN2 | 3.65 ± 0.59 | Tyrosine-protein phosphatase non-receptor |
   Rb1 | 3.50 ± 0.46 | Cell cycle exit, transcription factor |
   SRP40 | 2.88 ± 0.10 | Splicing factor |
   Sterol demethylase | 3.33 ± 0.33 | Sterols and steroids biosynthesis, oocyte maturation |
   Thiolase | 4.98 ± 0.32 | Trifunctional enzyme, acetyl-CoA transferase |
   TMEM79 | 3.01 ± 0.30 | Transmembrane protein, function unclear |
   TMP49 | 3.92 ± 0.42 | Transmembrane protein, function unknown |
   Transferase | 3.39 ± 0.58 | Arginine n-methyl-transferase |
   Bub3 | 4.85 ± 0.00 | Mitotic checkpoint protein |
   FAN | 3.28 ± 0.28 | Associated with N-SMase activation |
   Hsp1 | 11.02 ± 1.36 | Heat shock protein 1 |
   KPNA2 | 3.65 ± 0.36 | Importin alpha-2 subunit, |
   MCM3 | 3.00 ± 0.00 | DNA replication licensing factor 3 |
   MRPL47 | 3.33 ± 0.00 | Mitochondrial ribosomal protein L47 isoform b |
   NHL-domain II | 3.36 ± 0.59 | NHL-domain containing, unknown function |
   Ribonuclease | 4.15 ± 0.09 | Ribonuclease HI large subunit |
   sFRP-1 | 2.97 ± 0.55 | Wnt-signal regulator |
   TARBP2 | 3.05 ± 0.18 | TAR RNA-binding protein 2 |
   Tetraspanin-9 | 3.29 ± 0.00 | Transmembrane protein, interacts with integrins |
   USP1 | 3.25 ± 0.34 | Ubiquitin carboxyl-terminal hydrolase 1 |
Group 3: activators in RGCs | Â | Â |
   Ndrg3a | 3.73 ± 0.00 | N-myc downstream regulated 3, function unknown |
   Islet2 | 5.11 ± 0.22 | Insulin gene enhancer, transcription factor |
   Tetraspanin-31 | 3.00 ± 0.38 | Transmembrane protein, unknown function |
Group 4: repressors in RGCs | Â | Â |
   ELG protein | 0.27 ± 0.00 | mRNP complex, unknown function |
   Idax | 0.16 ± 0.01 | Negative regulation of Wnt signaling |
   NHL-protein | 0.27 ± 0.00 | NHL-domain containing, unknown function |
   RBM4L | 0.23 ± 0.01 | RRM-class RNA-binding protein |
   RBPMS2 | 0.20 ± 0.06 | RNA-binding protein RNP-1, unknown function |
   Zfp 161 | 0.23 ± 0.01 | Zinc finger, function unclear |
Ubiquitously expressed regulators | Â | Â |
   HMG | 2.93 ± 0.49 | HMG box DNA-binding domain |
   p65 TF | 6.16 ± 0.81 | NF-κB transcription factor p65 |
   Beta-actin | 0.27 ± 0.03 | Cytoskeleton |
   Tubulin alpha-1B chain | 3.28 ± 0.59 | Cytoskeleton |
   UBR2 | 3.18 ± .0.36 | Ubiquitin-protein ligase E3 component N-recognin-2 |
   Uncharacterized1 | 0.22 ± 0.01 | Unknown function |
   Coiled-coil domain | 3.25 ± 0.43 | Unknown function |
   EF-1-alpha | 3.31 ± 0.26 | Elongation factor |
   Nfkbia | 2.99 ± 0.44 | NF-kappaB inhibitor |
   Ankrd39 | 5.40 ± 0.71 | Ankyrin repeat domain-containing protein 39, unknown function |