| Â | PITA | PicTar |
|---|
Dataset | Percentage (ER- > ER+) | Percentage (ER- < ER+) | Spearman correlation | Percentage (ER- > ER+) | Percentage (ER- < ER+) | Spearman correlation |
|---|
HE | 58% | 23% | 0.861 | 77% | 12% | 0.752 |
MI | 100% | 0% | 0.646 | 60% | 16% | 0.778 |
MN | 73% | 10% | 0.668 | 62% | 17% | 0.763 |
VA | 86% | 2% | 0.659 | 65% | 5% | 0.578 |
WA | 68% | 18% | 0.855 | 59% | 22% | 0.837 |
- Percentage (ER- > ER+): the fraction of microRNAs with ARR < 1 and t-score < 0, indicating that the microRNAs show higher regulatory activity in ER- than in ER+ samples, as consistently supported by both the ARR method and RE-score expression comparison method. Percentage (ER- < ER+): the fraction of microRNAs with RR > 1 and t-score > 0. These microRNAs show higher regulatory activity in ER+ samples, as supported by both the ARR method and the RE-score expression comparison method. Spearman correlation: the correlation between the ARR value and t-score (ER-/ER+).
