Figure 1

Associations with the MHC in schizophrenia. The significance of case-control association studies, including those from three contributing groups (ISC, MGS, and SGENE), at the MHC region are shown. Recombination rate and gene annotation are also provided. The region shown is chromosome 6: 25-32 Mb. Only SNPs with P-values provided in meta-analysis are shown, although coverage and calculated P-values exist for many more SNPs in the MHC region. Although consensus from the meta-analysis associates chromosome 25.9-27.8 Mb near histone genes (rs13194053), ISC analysis shows rs3130375 to be most significant, whereas SGENE associates rs3131296. *Data not available.