Table 1 The 21 sequence-specific transcription factors studied
Factor | Symbol | DNA binding domain | Regulatory class |
|---|---|---|---|
Bicoid | BCD | Homeodomain | A-P early maternal |
Caudal | CAD | Homeodomain | A-P early maternal |
Giant | GT | bZip domain | A-P early gap |
Hunchback | HB | C2H2 zinc finger | A-P early gap |
Knirps | KNI | Receptor zinc finger | A-P early gap |
Kruppel | KR | C2H2 zinc finger | A-P early gap |
Huckebein | HKB | C2H2 zinc finger | A-P early terminal |
Tailless | TLL | Receptor zinc finger | A-P early terminal |
Dichaete | D | HMG/SOX class | A-P early gap-like |
Ftz | FTZ | Homeodomain | A-P pair rule |
Hairy | HRY | bHLH | A-P pair rule |
Paired | PRD | Homeodomain/paired domain | A-P pair rule |
Runt | RUN | Runt domain | A-P pair rule |
Sloppy paired 1 | SLP1 | Forkhead domain | A-P pair rule |
Daughterless | DA | bHLH | D-V maternal |
Dorsal | DL | NFkB/rel | D-V maternal |
Mad | MAD | SMAD-MH1 | D-V zygotic |
Medea | MED | SMAD-MH1 | D-V zygotic |
Schnurri | SHN | C2H2 zinc finger | D-V zygotic |
Snail | SNA | C2H2 zinc finger | D-V zygotic |
Twist | TWI | bHLH | D-V zygotic |