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Table 1 The 21 sequence-specific transcription factors studied

From: Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions

Factor Symbol DNA binding domain Regulatory class
Bicoid BCD Homeodomain A-P early maternal
Caudal CAD Homeodomain A-P early maternal
Giant GT bZip domain A-P early gap
Hunchback HB C2H2 zinc finger A-P early gap
Knirps KNI Receptor zinc finger A-P early gap
Kruppel KR C2H2 zinc finger A-P early gap
Huckebein HKB C2H2 zinc finger A-P early terminal
Tailless TLL Receptor zinc finger A-P early terminal
Dichaete D HMG/SOX class A-P early gap-like
Ftz FTZ Homeodomain A-P pair rule
Hairy HRY bHLH A-P pair rule
Paired PRD Homeodomain/paired domain A-P pair rule
Runt RUN Runt domain A-P pair rule
Sloppy paired 1 SLP1 Forkhead domain A-P pair rule
Daughterless DA bHLH D-V maternal
Dorsal DL NFkB/rel D-V maternal
Mad MAD SMAD-MH1 D-V zygotic
Medea MED SMAD-MH1 D-V zygotic
Schnurri SHN C2H2 zinc finger D-V zygotic
Snail SNA C2H2 zinc finger D-V zygotic
Twist TWI bHLH D-V zygotic
  1. A-P, anterior-posterior; D-V, dorsal-ventral.
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Genome Biology

ISSN: 1474-760X

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