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Figure 6 | Genome Biology

Figure 6

From: Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions

Figure 6

Highly bound regions are preferentially associated with genes transcribed and patterned in the blastoderm. Shown are the median distance of non-overlapping 200-peak cohorts to the closest gene belonging to each of three categories of gene: all genes (from genome release 4.3, March 2006; red lines); genes with known patterned expression (hand annotated based on Berkeley Drosophila Genome Project in situ images [23]; blue lines); and transcribed genes (defined by our RNA polymerase II (pol II) ChIP/chip binding [11]; green lines). Data are plotted down the ChIP/chip rank list to the 25% FDR threshold. The most highly bound regions are to the left along the x-axis and the location of 1% FDR threshold is indicated by a black, vertical dotted line. Shown are the results for the (a) DA 2, (b) HRY 2, (c) RUN 1, and (d) SNA 2 antibodies.

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Genome Biology

ISSN: 1474-760X

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