Figure 15

Heat map showing GO terms enriched in genes closest to regions bound by each factor. The seven most highly enriched GO terms associated with the closest genes to the 300 most highly bound peaks were determined for each of the 21 factors and the non-redundant set of all such terms identified. Each row shows the enrichment of each of these GO terms for one factor expressed as a normalized z score. The columns (GO terms) were arranged into three groups based on which of the three major regulatory classes of factor the GO terms are most enriched in, and are ranked from left to right based on the degree of this relative enrichment. (a) Results for the most highly bound 300 peaks (1-300); (b) results for the second most highly bound cohort of 300 peaks (301-600).