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Table 3 Enriched transcription factor binding sites identified in cluster 1 multi-species conserved elements

From: Motifs and cis-regulatory modules mediating the expression of genes co-expressed in presynaptic neurons

Transcription factor P-value FDR (%) Brief description
AP-2 0.002 0.08 Activating enhancer binding protein 2
ETF 0.006 0.23 TEA domain family member 2
CREB 0.008 0.32 cAMP responsive element binding protein
NRSF 0.008 0.33 RE1-silencing transcription factor
NGFI-C 0.009 0.36 Nerve growth factor/EGR4
MyoD 0.014 0.64 Myogenic differentiation 1
Olf-1 0.016 0.80 Olfactory neuronal TF 1
E2F 0.016 0.80 E2F family in control of cell cycle and tumor suppression
Myogenin 0.028 1.46 Myogenin/nuclear factor 1
NF-kappaB 0.028 1.46 Nuclear factor of kappa light polypeptide gene
c-Myc:Max 0.030 1.57 Myc proto-oncogene
Sp1 0.034 1.82 Trans-acting specific protein 1
AP-4 0.038 2.07 Activating enhancer binding protein 4
Nrf-1 0.039 2.08 Nuclear respiratory factor 1
HNF4 0.041 2.21 Hepatocyte nuclear factor 4
LXR 0.047 2.60 Liver × receptor
  1. The enrichment of 16 transcription factor binding sites over-represented in MCEs from cluster 1 genes in comparison to those in cluster 2 or 3 genes with a P-value < 0.05. FDR, false discovery rate.