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Figure 4 | Genome Biology

Figure 4

From: Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease

Figure 4

Adipose-hypothalamus network backbone. We define the network backbone as the bonds most visited by the all-pair shortest paths algorithm on the TTC network. In order to generate a robust backbone, we assigned P-values of Spearman correlations as bond weights. The subnetworks selected for further analysis are represented by a small number of representative genes on the backbone. Perturbing these genes most likely triggers responses in the complementary tissue.

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