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Table 5 Calculation of the MRCA of Ugandan type II and III isolates and reference strains based on the intron mutation rate

From: Whole genome sequencing of a natural recombinant Toxoplasma gondiistrain reveals chromosome sorting and local allelic variants

Chromosome Intron length* (bp) Minor SNPs in introns MRCA Me49/UgII (years) MRCA VEG/UgIII (years)
Type II     
   II 89,003 34 19,691  
   IV 85,471 58 34,979  
   VI 152,385 65 21,987  
   VIIa 198,902 28 7,256  
   IX 266,876 117 22,598  
   X 334,181 79 12,186  
   Total II 1,126,818 381 17,429  
Type III     
   Ia 80,522 2   1,280
   Ib 85,805 8   4,806
   III 82,660 9   5,612
   V 119,536 15   6,468
   VIIb 220,517 39   9,116
   VIII 337,557 78   11,911
   XII 352,605 78   11,403
   Total III 1,279,202 229   9,228
  1. The divergence between Ugandan and reference strains were calculated based on the intron mutation rate 1.94 × 10-8 [26]. A more comprehensive version is provided in Additional data file 4. *Length of intronic regions. MRCA, most recent common ancestor.