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Figure 3 | Genome Biology

Figure 3

From: Insights into the regulation of intrinsically disordered proteins in the human proteome by analyzing sequence and gene expression data

Figure 3

A summary of expression profiles for the highly disordered proteins. (a) The heat map displays four distinct transcript groups; constitutively expressed ribosomal subunits (light blue), high expressors (dark blue), medium expressors (green) and tissue specific expressors (gold). The clustering method was Ward's hierarchical clustering using Euclidean distances calculated over the absolute expression data matrix. Red colors indicate significantly high expression values (P < 0.001) within a sample tissue or cell line. (b). Summary of expression-function trends for highly disordered transcripts. Log10 of the number of tissues in which the transcript is expressed (x-axis); log10 expression of the average magnitude of expression within each tissue (y-axis). The points have been jittered for overlap using a normally distributed noise value of 0.05 on the log10 scale.

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