Pattern number |
A
|
SEPEA_NT1
|
GSEA
|
Maxmean
|
SEPEA_NT2
|
SEPEA_NT3
|
|---|
1 | 0.01 0.05 | 328 610 | 188 510 | 52 | 357 686 | 321 |
2 | 0.01 0.05 | 271 505 | 189 508 | 37 | 295 580 | 39 |
3 | 0.01 0.05 | 344 692 | 222 496 | 32 | 347 712 | 480 |
4 | 0.01 0.05 | 166 361 | 212 468 | 32 | 157 379 | 11 |
- Power estimates for the SEPEA_NT1, GSEA and SEPEA_NT2 methods (in terms of the number of experiments out of 1,000 that gave P-values for the randomization tests below nominal sizes of α = 0.01 and 0.05). The estimates for maxmean are given at an empirical size of 0.07 (nominal size of 0.001) and those for SEPEA_NT3 at an empirical size of 0.05 (nominal size of 0.001). These are results from simulations in which the treatment resulted in an over-expression of the mean expression of the target genes by the factor pert = 1.2. The methods were evaluated on correlation patterns 1-4.
