Figure 3
Mutation in 3D7attB histone 2B. (a) Plot of -log P-value for z-test (blue line) performed with 3D7attB versus the 3D7 reference detected a polymorphism in the histone 2B gene with a P-value cutoff of 1 × 10-8 (black line). (b) Sequencing of the histone 2B gene in 3D7attB revealed two consecutive point mutations resulting in a coding nonsynonymous mutation.